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Simultaneously, metformin activates the LKB1/AMPK signaling pathway, leading to the inhibition of aerobic glycolysis in cells, as well as the insulin-like growth factor-1(IGF-1) signaling pathway and mTOR pathway in EC cells

10 GCL is composed of two subunits: a heavy, catalytic subunit (GCLC) and a light, modifier subunit

The 3-nontranslated region of rat renal glutaminase mRNA contains a pH-responsive stability element